Asparagine

Asparagine is known worldwide as the first amino acid that was isolated from its natural source. Back in 1806, Asparagine was isolated from asparagus juice by Pierre Jean Robiquet and Louis-Nicolas Vauquelin.

Chemical Structure
structure of Asparagine

IUPAC Name: (2S)-2,4-Diamino-4-oxobutanoic acid
Symbol: Three-letter code - Asn. One-letter code - N
Molecular Weight (Molar Mass): 132.11792 g/mol
Molecular Formula (Structural Formula): C4H8N2O3
Canonical SMILES: C(C(C(=O)O)N)C(=O)N
Isomeric SMILES: C([C@@H](C(=O)O)N)C(=O)N
InChIKey Identifier: DCXYFEDJOCDNAF-VYAUFGAVDT
CAS Number: 70-47-3
MDL Number: MFCD00064401
Melting point: 235 °C
Solubility in water: 20 g/L (20 °C); pKa - 2,02; pKb - 8,80
2D Molfile: Get the molfile
3D PDB file: Get the PDB file
Other names: (S)-2-Aminosuccinic acid 4-amide; alpha-Aminosuccinamic acid; L-Aspartic acid 4-amide; (2S)-2-Amino-3-carbamoyl-propanoic acid


Asparagine is also known for its key role in the biosynthesis of glycoproteins. In addition, it is also essential for the synthesis of many other proteins. Human nervous system also needs this amino acid to be able to maintain an equilibrium. Asparagine increases the resistance to fatigue and improves the smooth functioning of the liver. So, Asparagine benefits work best in the field of nervine health and liver protection.

Currently, Asparagine is one of the twenty most common amino acids on our planet - one of the principal and the most abundant elements that help to transport nitrogen. Besides, this amino acid is required by human body cells for the protein production. It can be produced in the liver and is recognized worldwide for its ability to help increase the resistance to fatigue, thus improving athletic stamina.

This amino acid is actually an essential component of proteins involved in signaling, neuronal development and transmission across nerve endings. It is also necessary for transformation of amino acid from one form to another. In addition, Asparagine is known for its key role in the biosynthesis of glycoproteins, as well as in the synthesis of many other proteins.

The most common typical dietary sources of this amino acid include beef, chicken, dairy products, seafood, and eggs. As for vegetarians, they may find helpful to consume asparagus, soy, and whole grains to get more amino acid from them.

People experiencing a deficiency of Asparagine may suffer from poor metabolism and show inability to manufacture and excrete urea, which is waste product of excess dietary protein. Such people thus may reveal symptoms like depression, confusion, and headaches. In addition, among the main benefits of Asparagine you can find the facts that it may help in metabolizing ammonia in the human body and enable proper functioning of the liver, as well as it enables a robust system resistant to fatigue.